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Markus Müller Selected Research

tariquidar (XR9576)

12/2019Assessment of brain delivery of a model ABCB1/ABCG2 substrate in patients with non-contrast-enhancing brain tumors with positron emission tomography.
4/2013Tariquidar and elacridar are dose-dependently transported by P-glycoprotein and Bcrp at the blood-brain barrier: a small-animal positron emission tomography and in vitro study.
11/2012Synthesis and preclinical evaluation of the radiolabeled P-glycoprotein inhibitor [(11)C]MC113.
1/2012A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer.
6/2011A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier.
8/2010Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor.
12/2009A pilot study to assess the efficacy of tariquidar to inhibit P-glycoprotein at the human blood-brain barrier with (R)-11C-verapamil and PET.

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Markus Müller Research Topics

Disease

31Neoplasms (Cancer)
05/2022 - 01/2002
12Breast Neoplasms (Breast Cancer)
12/2019 - 07/2010
10Prostatic Neoplasms (Prostate Cancer)
01/2018 - 05/2002
10Infections
06/2012 - 01/2002
8Soft Tissue Infections
09/2007 - 05/2003
7Urinary Bladder Neoplasms (Bladder Cancer)
01/2019 - 01/2002
6Inflammation (Inflammations)
01/2017 - 11/2002
5Melanoma (Melanoma, Malignant)
10/2020 - 01/2003
5Epilepsy (Aura)
01/2015 - 09/2007
4Carcinoma (Carcinomatosis)
07/2022 - 01/2002
4Pain (Aches)
12/2021 - 04/2004
4Human Influenza (Influenza)
09/2012 - 01/2009
4Teratoma (Teratoid Tumor)
08/2005 - 09/2002
3Critical Illness (Critically Ill)
01/2020 - 05/2003
3Brain Neoplasms (Brain Tumor)
12/2019 - 10/2012
3Lymphoma (Lymphomas)
01/2018 - 06/2014
3Drug-Related Side Effects and Adverse Reactions
09/2015 - 02/2005
3Temporal Lobe Epilepsy
10/2014 - 09/2007
3Alzheimer Disease (Alzheimer's Disease)
01/2012 - 09/2006
3Carcinogenesis
08/2005 - 09/2002
3Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
06/2005 - 09/2002
3Sertoli Cell-Only Syndrome
06/2004 - 08/2002
2Renal Cell Carcinoma (Grawitz Tumor)
07/2022 - 06/2002
2Thrombosis (Thrombus)
01/2022 - 01/2020
2AIDS-Related Lymphoma (Lymphoma, AIDS Related)
01/2018 - 02/2012
2Lymphatic Metastasis
05/2016 - 09/2004
2Cardiovascular Diseases (Cardiovascular Disease)
11/2015 - 11/2002
2Headache (Headaches)
08/2013 - 06/2008
2Renal Insufficiency (Renal Failure)
08/2013 - 03/2010
2Insulin Resistance
12/2012 - 06/2008
2Status Epilepticus (Complex Partial Status Epilepticus)
10/2012 - 06/2011
2Hemorrhage
02/2012 - 08/2005
2Diabetes Mellitus
11/2011 - 03/2010
2African Trypanosomiasis (Nagana)
01/2011 - 06/2009
2Body Weight (Weight, Body)
12/2009 - 01/2008
2Wounds and Injuries (Trauma)
08/2009 - 11/2007
2Pneumonia (Pneumonitis)
10/2008 - 12/2005
2Pulmonary Atelectasis
10/2008 - 12/2005
2Type 2 Diabetes Mellitus (MODY)
06/2008 - 01/2008
2Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2008 - 07/2003
2Sepsis (Septicemia)
01/2007 - 07/2002
2Peripheral Arterial Disease
11/2006 - 07/2005
2Infertility (Sterility)
04/2005 - 06/2004
2Bacterial Infections (Bacterial Infection)
02/2005 - 07/2002
2Sexually Transmitted Diseases (Sexually Transmitted Disease)
10/2003 - 05/2003
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
05/2022
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
05/2022
1Frontotemporal Dementia (Semantic Dementia)
01/2022

Drug/Important Bio-Agent (IBA)

17Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2003
14Messenger RNA (mRNA)IBA
01/2020 - 05/2002
13Pharmaceutical PreparationsIBA
05/2022 - 07/2002
13Member 1 Subfamily B ATP Binding Cassette TransporterIBA
12/2019 - 09/2007
7tariquidar (XR9576)IBA
12/2019 - 12/2009
7VaccinesIBA
08/2013 - 06/2008
7Anti-Bacterial Agents (Antibiotics)IBA
10/2008 - 07/2002
6Verapamil (Calan)FDA LinkGeneric
10/2014 - 09/2007
5DNA (Deoxyribonucleic Acid)IBA
10/2012 - 02/2002
5Telomerase (Telomerase Reverse Transcriptase)IBA
11/2005 - 01/2002
5SurvivinIBA
08/2005 - 06/2004
4Ciprofloxacin (Cipro)FDA LinkGeneric
01/2016 - 12/2002
4Glucose (Dextrose)FDA LinkGeneric
12/2012 - 07/2009
4Prostate-Specific Antigen (Semenogelase)IBA
01/2009 - 05/2002
3RNA (Ribonucleic Acid)IBA
01/2022 - 09/2004
3HLA Antigens (Human Leukocyte Antigens)IBA
10/2020 - 01/2017
3Peptides (Polypeptides)IBA
10/2020 - 01/2017
3Anticonvulsants (Antiepileptic Drugs)IBA
10/2014 - 09/2007
3Rituximab (Mabthera)FDA Link
10/2014 - 09/2011
3ElacridarIBA
04/2013 - 04/2011
3Cefpirome (HR 810)IBA
02/2005 - 01/2002
2Biological ProductsIBA
12/2021 - 01/2007
2Neoplasm Antigens (Tumor Antigens)IBA
10/2020 - 01/2020
2Adenosine Triphosphate (ATP)IBA
03/2018 - 08/2013
2Docetaxel (Taxotere)FDA Link
01/2017 - 08/2007
2Insulin (Novolin)FDA Link
12/2012 - 01/2008
2Pilocarpine (Ocusert)FDA LinkGeneric
10/2012 - 06/2011
2VancomycinFDA LinkGeneric
08/2009 - 04/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2009 - 11/2002
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
02/2008 - 01/2003
2Small Interfering RNA (siRNA)IBA
08/2007 - 01/2003
2Anti-Infective Agents (Microbicides)IBA
04/2006 - 07/2002
2FluoroquinolonesIBA
12/2005 - 02/2005
2Levofloxacin (Levaquin)FDA Link
12/2005 - 05/2004
2Biomarkers (Surrogate Marker)IBA
11/2005 - 03/2002
2RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
11/2005 - 07/2003
2Glutathione Transferase (Glutathione S-Transferase)IBA
11/2003 - 03/2002
2EnzymesIBA
11/2002 - 09/2002
2RibonucleoproteinsIBA
11/2002 - 09/2002
1NucleosidesIBA
05/2022
1DecitabineFDA Link
05/2022

Therapy/Procedure

21Therapeutics
07/2022 - 07/2002
8Drug Therapy (Chemotherapy)
01/2018 - 01/2002
4Prostatectomy (Retropubic Prostatectomy)
08/2005 - 05/2002
3Critical Care (Surgical Intensive Care)
07/2018 - 05/2003
3Castration
01/2018 - 05/2016
2Heart-Assist Devices
09/2020 - 01/2020
2Cystectomy
01/2019 - 05/2002
2Intravenous Administration
12/2012 - 12/2009
2Coronary Artery Bypass (Coronary Artery Bypass Surgery)
10/2008 - 11/2006
2Catheters
07/2002 - 01/2002
1Liver Transplantation
01/2022